A positive Hoffman's reflex may indicate an upper motor neuron lesion or a pyramidal sign Hoffmann's reflex may be seen in the following conditions Multiple sclerosis ALS Diseases which cause spinal cord compression (myelopathy) such as cervical spondylitis, tumors, or degenerative arthritisPatient with cervical myelopathy demonstrating Hoffman's and inverted brachioradialis reflex Cord compression seen as evidenced by effacement of cerebrospin During a standard neurological exam, the Hoffman sign is common, and a positive sign can aid in the diagnosis However, a 18 systematic review, with level 1 evidence, on the utility of the Hoffman sign for the diagnosis of degenerative cervical myelopathy found insufficient data to support the use of the exam alone to confirm or refute a diagnosis of degenerative
Cervical Radiculopathy And Myelopathy Wayne Cheng Md Instructor